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Gao Changyou

Professor, Department of Polymer Science and Engineering

 

Phone: +86 571 8795 1108
Fax: +86 571 8795 1108
Email: cygao@zju.edu.cn; cygao@mail.hz.zj.cn
Office: The Polymer Building

Zhejiang University, Yuquan Campus
38 Zheda Road
Hangzhou, China 310027

 

Other Appointments

Deputy Director, Institute of Biomedical Macromolecules
Deputy Director, Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education

 

Professional Activities

An Editorial Member of
Journal of Zhejiang University: Science
Journal of Tissue Engineering and Reconstructive Surgery
Chinese Science Bulletin, Science in China: Chemistry
Progress in Chemistry
Journal of Nanoscience Letters
Colloids and Surfaces B: Biointerfaces
A Committee member of
Chinese Society of Biomedical Engineering, Biomaterials Division
Chinese Society of Biomedical Engineering, Tissue Engineering Division
Chinese Materials Research Society, Biomaterials Division
Chinese Society for Composite Materials, Composite Biomaterials Division

 

Education

Ph.D. – Jilin University, Polymer Chemistry and Physics, 1996
M. S – Jilin University, Polymer Chemistry and Physics, 1993
B.S. – Jilin University, Polymer Materials and Engineering, 1990

Working Experience

2001-, Prof. Department of Polymer Science and Engineering, Zhejiang University
1999-2004 (18months in total), Visiting Scholar, Max Planck Institute of Colloids and Interfaces, Germany
1999- DAAD fellowship, Max Planck Institute of Colloids and Interfaces, Germany
1998-2001, Associate Prof., Department of Polymer Science and Engineering, Zhejiang University
1996-1998, Postdoc, Department of Polymer Science and Engineering, Zhejiang University
 

Awards and Honors

The National Science Fund for Distinguished Young Scholars of China, 2004
A Cheung Kong Scholar of Ministry of Education of China, 2008
The first level award of Science and Technology of Zhejiang Province, 2008
The second level award of Science and Technology of Zhejiang Province, 2010
 

Research Interests

Biomedical materials for tissue engineering and regenerative medicine
Colloidal and nano-biomaterials for drug delivery and cellular interaction
 

Current Projects

  1. Key Project of National Natural Science Foundation of China. Study on gradient biomedical polymers for mediating cell migration and differentiation, 2010.1-2013.12
  2. Partner of Frame Work Program 7 (FP 7). Health Impact of Engineered Metal and Metal Oxide Nanoparticles: Response, Bioimaging and Distribution at Cellular and Body LevelúČ2009.10-2012.9
  3. Partner of 973 Project. Characteristics of the surfaces and interfaces of tissue inductive biomaterials and their interactions with biological system in a cellular and protein level, 2011.1-2015.12
  4. The Ministry of Science and Technology of China for the Indo-China Cooperation. Structure design and functionalization of self-assembled microcapsules for drug delivery, 2010.1-2013.6

Publications
 

  1. Yuying Zhang, Bing Wang, Xinan Meng, Guanqing Sun, Changyou Gao*. Influences of Acid-Treated Multiwalled Carbon Nanotubes on Fibroblasts: Proliferation, Adhesion, Migration, and Wound Healing, Annals of Biomedical Engineering, 2011, 39(1): 414-426
  2. Rui Guo, Shaojun Xu, Lie Ma,*, Aibin Huang, Changyou Gao*. The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagenechitosan dermal equivalents, Biomaterials, 2011, 32: 1019-1031.
  3. Wei Wang, Bo Li, Junzhou Yang, Long Xin, Yanglin Li, Hongpin Yin, Yiying Qi, Yangzi Jiang, Hongwei Ouyang, Changyou Gao*. The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs, Biomaterials, 2010, 31: 8964-8973.
  4. Yuying Zhang, Ling Hu, Dahai Yu, Changyou Gao*. Influence of silica particle internalization on adhesion and migration of human dermal fibroblasts, Biomaterials 2010, 31: 8465-8474.
  5. Rui Guo, Shaojun Xu, Lie Ma*, Aibin Huang, Changyou Gao*. Enhanced angiogenesis of gene-activated dermal equivalent for treatment of full thickness incisional wounds in a porcine model, Biomaterials, 2010, 31: 7308-7320.
  6. Jie Yang, Changyou Gao*. Fabrication of Diverse Microcapsule Arrays of High Density and Good Stability, Macromolecular Rapid Communications, 2010, 31(12): 1065-1070.
  7. Weijun Tong , Yi Zhu , Zhipeng Wang, Changyou Gao*, Helmuth M?hwald. Micelles-Encapsulated Microcapsules for Sequential Loading of Hydrophobic and Water-Soluble Drugs, Macromolecular Rapid Communications, 2010, 31(11): 1015-1019.
  8. Wei Wang, Bo Li, Yanglin Li, Yangzi Jiang, Hongwei Ouyang, Changyou Gao*. In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes, Biomaterials 2010, 31: 5953-5965
  9. Jie Zhou, Gabriela Romero, Elena Rojas, Lie Ma, Sergio Moya*, Changyou Gao*. Layer by layer chitosan/alginate coatings on poly(lactide-co-glycolide) nanoparticles for antifouling protection and Folic acid binding to achieve selective cell targeting, Journal of Colloid and Interface Science 2010, 345: 241–247.
  10. Huaping Tan, Jindan Wu, Dejuan Huang, Changyou Gao*. The Design of Biodegradable Microcarriers for Induced Cell Aggregation, Macromol. Biosci. 2010, 10: 156-163.
  11. Jie Zhou, Gabriela Romero, Elena Rojas, Sergio Moya,* Lie Ma, Changyou Gao*. Folic Acid Modified Poly(lactide-co-glycolide) Nanoparticles, Layer-by-Layer Surface Engineered for Targeted Delivery, Macromolecular Chemistry and Physics, 2009, 211: 404-411. Cover
  12. Bo Wang, Zhengwei Mao, Xinan Meng, Weijun Tong, Changyou Gao*. Fabrication of cellular polycaprolactone films for cell culture, Colloids and Surfaces B: Biointerfaces, 2010, 76: 38–43.
  13. Zhengwei Mao, Li Wan, Ling Hu, Lie Ma, Changyou Gao*. Tat peptide mediated cellular uptake of SiO2 submicron particles, Colloids and Surfaces B: Biointerfaces, 2010, 75: 432–440.
  14. Gabriela Romero, Irina Estrela-Lopis, Jie Zhou, Elena Rojas, Ana Franco, Christian Sanchez Espinel, Africa Gonzlez Fernndez, Changyou Gao, Edwin Donath, and Sergio E. Moya*. Surface Engineered Poly(lactide-co-glycolide) Nanoparticles for Intracellular Delivery: Uptake and Cytotoxicity - A Confocal Raman Microscopic Study, Biomacromolecules, 2010, 11(11): 2993-2999.
  15. Xianyan Yang, Yilai Gan, Xin Gao, Li Zhao, Changyou Gao, Xinli Zhang, Yanbo Feng, Kang Ting, Zhongru Gou*. Preparation and characterization of trace elements-multidoped injectable biomimetic materials for minimally invasive treatment of osteoporotic bone trauma, Journal of Biomedical Materials Research Part A, 2010, 95A (4): 1170-1181.
  16. Chen Zong, Deting Xue, Wenji Yuan, Wei Wang, Dan Shen, Xiangmin Tong, Dongyan Shi, Liyue Liu, Qiang Zheng, Changyou Gao, and Jinfu Wang*. Reconstruction of rat calvarial defects with human mesenchymal stem cells and osteoblast-like cells in polylactide-co-glycolic acid scaffolds, European Cells and Materials, 2010, 20: 109-120.
  17. Jun Li, Ran Tao, Wei Wu, Hongcui Cao, Jiaojiao Xin, Jun Li, Jing Guo, Longyan Jiang, Changyou Gao, Achilles A.Demetriou, Daniel L. Farkas, Lanjuan Li *. 3D PLGA Scaffolds Improve Differentiation and Function of Bone Marrow Mesenchymal Stem Cell-Derived Hepatocytes, Stem cell and Development, 2010, 19 (9): 1427-1436.
  18. Xianyan Yang, Xin Gao, Yilai Gan, Changyou Gao, Xinli Zhang, Kang Ting, Benjamin M. Wu, Zhongru Gou*. Facile Synthesis of Octacalcium Phosphate Nanobelts: Growth Mechanism and Surface Adsorption Properties, Journal of Physical Chemistry C, 2010, 114 (14): 6265–6271.
  19. Jinfeng Yang, Cheng Cao, Wei Wang, Xiangmin Tong, Dongyan Shi, Fabai Wu, Qiang Zheng, Chunjuan Guo, Zhijun Pan, Changyou Gao, Jinfu Wang*. Proliferation and osteogenesis of immortalized bone marrow-derived mesenchymal stem cells in porous polylactic glycolic acid scaffolds under perfusion culture, J Biomed Mater Res 2010, 92A: 817–829.
  20. Xiaohong Hu, Lie Ma, Chengchao Wang, Changyou Gao*. Gelatin Hydrogel Prepared by Photo-initiated Polymerization and Loaded with TGF-?1 for Cartilage Tissue Engineering, Macromol. Biosci. 2009, 9, 1194–1201.
  21. Xiao Gong and Changyou Gao*. Influence of salt on assembly and compression of PDADMAC/PSSMA polyelectrolyte multilayers, Phys. Chem. Chem. Phys., 2009, 11, 11577–11586.
  22. Zhiqiang Feng, Changyou Gao*, Jiacong Shen. Spontaneous Deposition of FITC-Labeled Dextran into Covalently Assembled (PGMA/PAH)4 Microcapsules, Macromolecular Chemistry and Physics, 2009, 210(17): 1387-1393. Cover
  23. Huaping Tan, Dejuan Huang, Lihong Lao, Changyou Gao*. RGD Modified PLGA/Gelatin Microspheres as Microcarriers for Chondrocyte Delivery, Journal of Biomedical Materials Research Part B, Applied Biomaterials, 2009, 91B (2): 228-238
  24. Zhengwei Mao, Haifei Shi, Rui Guo, Lie Ma,* Changyou Gao*, Chunmao Han, Jiacong Shen. Enhanced angiogenesis of porous collagen scaffolds by incorporation of TMC/DNA complexes encoding vascular endothelial growth factor, Acta Biomaterialia, 2009, 5: 2983–2994.
  25. JinDan Wu, HuaPing Tan, LinHui Li and ChangYou Gao*. Covalently immobilized gelatin gradients within three-dimensional porous scaffolds, Chinese Science Bulletin, 2009, 54(18): 3174-3180
  26. Zhongru Gou, Xianyan Yang, Xin Gao, Xinli Zhang, Kang Ting, Benjamin M. Wu and Changyou Gao, CrystEngComm, 2009, 11, 1585-1590
  27. Ling Hu, Zhengwei Mao and Changyou Gao*. Colloidal particles for cellular uptake and delivery [Hihglight article], Journal of Materials Chemistry, 2009, 19, 3108-3115
  28. Jie Zhou, Sergio Moya,* Lie Ma, Changyou Gao,* Jiacong Shen. Polyelectrolyte Coated PLGA Nanoparticles: Templation and Release Behavior, Macromolecular Bioscience, 2009, 9: 326-335
  29. Lulu Han, Jing Zhou, Xiao Gong, Changyou Gao*. Solvent-assisted polymer micro-molding, Chinese Science Bulletin, 2009, 54 (13): 2193-2204
  30. Zhiqiang Feng, Guoqiang Fan, Hongxia Wang, Changyou Gao,* Jiacong Shen. Polyphosphazene Microcapsules Fabricated through Covalent Assembly, Macromol. Rapid Commun. 2009, 30 (6): 448-452
  31. Haiguang Zhao, Lie Ma*, Changyou Gao*, Jiacong shen. A Composite Scaffold of PLGA Microspheres/Fibrin Gel for Cartilage Tissue Engineering: Fabrication, Physical Properties, and Cell Responsiveness, Journal of Biomedical Materials Research Part B, Applied Biomaterials, 2009, 88B (1): 240-249
  32. Jie Yang, Changyou Gao*. Fabrication of microcapsule arrays on chemically patterned surfaces via covalent linking, Journal of Zhejiang University Science A, 2009, 10(1): 114-120
  33. Huaping Tan, Jindan Wu, Lihong Lao, Changyou Gao*. Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering, Acta Biomaterialia, 2009, 5: 328-337
  34. Xiao Gong, Jie Yang, Lulu Han, Changyou Gao*. Influence of Drying Time of Polyelectrolyte Multilayers on the Compression-Induced Pattern Formation, Langmuir, 2008, 24(24): 13925-13933
  35. Linhui Li, Yang Zhu, Bo Li, Changyou Gao*. Fabrication of Thermoresponsive Polymer Gradients for Study of Cell Adhesion and Detachment, Langmuir, 2008, 24, 13632-13639
  36. Haifei Shi, Chunmao Han*, Zhengwei Mao, Lie Ma, Changyou Gao. Enhanced Angiogenesis in Porous Collagen-Chitosan Scaffolds Loaded with Angiogenin, Tissue Engineering Part A, 2008, 14(11): 1775-1785
  37. Jie Yang, Changyou Gao*. Progress in fabricating arrays of soft spherical vessels on mesoscale with spatial control, Chinese Science Bulletin, 2008, 53 (22): 3477-3490
  38. Huaping Tan, Li Wan, JindanWu, Changyou Gao*. Microscale control over collagen gradient on poly(L-lactide) membrane surface for manipulating chondrocyte distribution, Colloids and Surfaces B: Biointerfaces, 2008, 67: 210–215
  39. Lihong Lao, Huaping Tan, YingjunWang, Changyou Gao*. Chitosan modified poly(l-lactide) microspheres as cell Microcarriers for cartilage tissue engineering, Colloids and Surfaces B: Biointerfaces, 2008, 66: 218–225
  40. Yi Zhu, Weijun Tong, Changyou Gao*, Helmuth M?hwald. Assembly of polymeric micelles into hollow microcapsules with extraordinary stability against extreme pH conditions, Langmuir, 2008, 24: 7810-7816
  41. Xiaohong Hu, Jie Zhou, Nan Zhang, Huaping Tan, Changyou Gao*. Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles/chitosan hydrogel, Journal of the Mechanical Behavior of Biomedical Materials, 2008, 1 (4): 352-359.
  42. Weijun Tong, Changyou Gao*. Multilayer microcapsules with tailored structures for bio-related applications [review], Journal of Materials Chemistry, 2008, 18: 3799–3812
  43. Zhipeng Wang, Zhiqiang Feng, Changyou Gao*. Stepwise assembly of the same polyelectrolytes using host-guest interaction to obtain microcapsules with multiresponsive properties, Chemistry of Materials, 2008, 20(13): 4194-4199
  44. Yi Hong, Yihong Gong, Changyou Gao*, Jiacong Shen. Collagen-coated polylactide microcarriers/chitosan hydrogel composite: Injectable scaffold for cartilage regeneration, Journal of Biomedical Materials Research Part A, 2008, 85A (3): 628-637
  45. Jie Zhou, Bo Wang, Weijun Tong Elena Maltseva, Gang Zhang, Rumen Krastev, Changyou Gao*, Helmuth M?hwald, Jiacong Shen. Influence of assembling pH on the stability of poly(L-glutamic acid) and poly(L-lysine) multilayers against urea treatment, Colloids and Surfaces B: Biointerfaces, 2008, 62: 250–257
  46. Yi Zhu, Weijun Tong, Changyou Gao* and Helmuth Mo¨hwald. Fabrication of bovine serum albumin microcapsules by desolvation and destroyable crosslinking, J. Mater. Chem., 2008, 18 (10), 1153-1158
  47. Bo Wang, Miao Wang, Hao Zhang, Nelli S. Sobal, Weijun Tong, Changyou Gao*, Yanguang Wang, Michael Giersig, Dayang Wang* Helmuth M?hwald. Stepwise interfacial self-assembly of nanoparticles via specific DNA pairing, Phys. Chem. Chem. Phys., 2007, 9: 6313–6318. Cover article.
  48. Zhiqiang Feng, Zhipeng Wang, Changyou Gao*, Jiacong Shen. Direct Covalent Assembly to Fabricate Microcapsules with Ultrathin Walls and High Mechanical Strength, Advanced Materials, 2007, 19 (21): 3687-3691
  49. Zuwei Ma, Zhengwei Mao, Changyou Gao?. Surface modification and property analysis of biomedical polymers used for tissue engineering [Review], Colloids and Surfaces B: Biointerfaces, 2007 (60): 137-157
  50. Zhiqiang Feng, Zhipeng Wang, Changyou Gao*, Jiacong Shen. Template Polymerization to Fabricate Hydrogen-Bonded Poly(acrylic acid)/Poly(vinylpyrrolidone) Hollow Microcapsules with a pH-Mediated Swelling-Deswelling Property, Chem. Mater. 2007, 19, 4648-4657
  51. Zhengwei Mao, Bo Wang, Lie Ma, Changyou Gao* and Jiacong Shen. The influence of polycaprolactone coating on the internalization and cytotoxicity of gold nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine, 2007, 3: 215-223
  52. Lie Ma, Jie Zhou, Changyou Gao*, Jiacong Shen. Incorporation of Basic Fibroblast Growth Factor by a Layer-by-Layer Assembly Technique to Produce Bioactive Substrates, Journal of Biomedical Materials Research part B: Appl Biomater, 2007, 83B: 285-292
  53. Yihong Gong, Yabin Zhu, Yunxiao Liu, Zuwei Ma, Changyou Gao*, Jiacong Shen. Layer-by-layer assembly of chondroitin sulfate and collagen on aminolyzed poly(l-lactic acid) porous scaffolds to enhance their chondrogenesis, Acta Biomaterialia, 2007, 3: 677-685
  54. Zhengwei Mao, Lie Ma*, Jiang Yan, Ming Yan, Changyou Gao*, Jiacong Shen. The gene transfection efficiency of thermoresponsive N,N,N-trimethyl chitosan chloride-g-poly(N-isopropylacrylamide) copolymer, Biomaterials, 2007, 28: 4488-4500
  55. Yihong Gong, Lijuan He, Jun Li, Qingliang Zhou, Zuwei Ma, Changyou Gao*, Jiacong Shen. Hydrogel-filled polylactide porous scaffolds for cartilage tissue engineering, Journal of Biomedical Materials Research part B, 2007, 82B: 192-204
  56. Yihong Gong, Qingliang Zhou, Changyou Gao*, Jiacong Shen. In vitro and in vivo degradability and cytocompatibility of poly(L-lactic acid) scaffold fabricated by gelatin particle leaching method, Acta Biomaterialia, 2007, 3: 531-540
  57. Zhengwei Mao, Lie Ma,* Yan Jiang, Ming Yan, Changyou Gao,* Jiacong Shen. N,N,N-trimethyl chitosan chloride as a gene vector: synthesis and application, Macromolecular Bioscience, 2007, 7, 855-863
  58. Yunxiao Liu, Tao He, Haiqing Song, Changyou Gao*. Layer-by-layer assembly of biomacromolecules on poly(ethylene terephthalate) films and fiber fabrics to promote endothelial cell growth, Journal of Biomedical Materials Research, 2007, 81A: 692-704
  59. Qinghe Zhao, Baosan Han, Zhaohai Wang, Changyou Gao*, Chenghong Peng, Jiacong Shen. Hollow chitosan-alginate multilayer microcapsules as drug delivery vehicle: doxorubicin loading and in vitro and in vivo studies, Nanomedicine: Nanotechnology, Biology, and Medicine, 2007, 3: 63-74
  60. Bo Wang, Yi Hong, Jie Feng, Yihong Gong, Changyou Gao*. Rings of Hydrogel Fabricated by a Micro-Transfer Technique, Macromol. Rapid Commun. 2007, 28, 567-571
  61. Feng Wang, Jun Feng, Weijun Tong, Changyou Gao*. A facile pathway to fabricate microcapsules by in situ polyelectrolyte coacervation on poly(styrene sulfonate)-doped CaCO3 particles, J. Mater. Chem., 2007,17, 670-676
  62. Yi Hong, Haiqing Song, Yihong Gong, Zhengwei Mao, Changyou Gao*, Jiacong Shen. Covalently crosslinked chitosan hydrogel: Properties of in vitro degradation and chondrocyte encapsulation, Acta Biomaterialia, 2007, 3:23-31
  63. Weijun Tong, Changyou Gao*, Helmuth M?hwald. Single Polyelectrolyte Microcapsules Fabricated By Glutaraldehyde-Mediated Covalent Layer-By-Layer Assembly, Macromolecular Rapid Communications, 2006, 27 (24): 2078-2083.
  64. Yi Hong, Zhengwei Mao, Hualin Wang, Changyou Gao*, Jiacong Shen. Covalently crosslinked chitosan hydrogel formed at neutral pH and body temperature, Journal of Biomedical Materials Research, 2006, 79A: 913-922.
  65. Weijun Tong, haiqing Song, Changyou Gao*, Helmuth M?hwald. Equilibrium Distribution of Permeants in Polyelectrolyte Microcapsules Filled with Negatively Charged Polyelectrolyte: The Influence of Ionic Strength and Solvent Polarity, Journal of Physical Chemistry B, 2006, 110: 12905-12909
  66. Bo Wang, Ke Chen, Shan Jiang, Fran?ois Reincke, Weijun Tong, Dayang Wang, Changyou Gao*. Chitosan-Mediated Synthesis of Gold Nanoparticles on Patterned Poly(dimethylsiloxane) Surfaces, Biomacromolecules, 2006, 7, 1203-1209
  67. Bo Wang, Lili Liu, Ke Chen, Lin Chen, Jie Feng, Changyou Gao*. Compression-Inhibited Pore Formation of Polyelectrolyte Multilayers Containing Weak Polyanions: A Scanning Force Microscopy Study, ChemPhysChem, 2006, 7: 590-596
  68. Bo Wang, Qinghe Zhao, Feng Wang, Changyou Gao*. Biologically Driven Assembly of Polyelectrolyte Microcapsule Patterns To Fabricate Microreactor Arrays, Angew. Chem. Int. Ed., 2006, 45: 1560-1563
  69. Weijun Tong, Changyou Gao,* Helmuth M?hwald. Stable weak polyelectrolyte microcapsules with pH-responsive permeability, Macromolecules, 2006, 39, 335-340
  70. Bingbing Jiang, Ling Hu, Changyou Gao*, Jiacong Shen. Crosslinked polysaccharide nanocapsules: Preparation and drug release properties, Acta Biomaterialia, 2006, 2(1): 9-18
  71. Bo Wang, Tao He, Lili Liu, Changyou Gao*. Poly(ethylene glycol) micro-patterns as environmentally sensitive template for selective or non-selective adsorption, Colloids and Surfaces B: Biointerfaces 2005, 46(3):, 169-174
  72. Xingyu Liu, Changyou Gao*, Jiacong Shen, Helmuth M?hwald. Multilayer Microcapsules as Anti-Cancer Drug Delivery Vehicle: Deposition, Sustained Release, and in vitro Bioactivity, Macromolecular Bioscience, 2005, 5(12): 1209-1219
  73. Yunxiao Liu, Tao He, Changyou Gao*. Surface modification of poly(ethylene terephthalate) via hydrolysis and layer-by-layer assembly of chitosan and chondroitin sulfate to construct cytocompatible layer for human endothelial cells, Colloids and Surfaces B: Biointerfaces, 2005, 46 (2): 117-126
  74. Bingbing Jiang, Ling Hu, Changyou Gao*, Jiacong Shen. Ibuprofen-loaded nanoparticles prepared by a co-precipitation method and their release properties, International Journal of Pharmaceutics, 2005, 304, (1-2), 220-230.
  75. Bo Chen, Changyou Gao*. Robust poly(allylamine)-graft-poly(Nisopropylacrylamide) particles prepared by physical crosslinking with poly(styrene sulfonate), Macromolecular Rapid Communications, 2005, 26, 1657-1663.
  76. Zhengwei Mao, Lie Ma, Jie Zhou, Changyou Gao,* and Jiacong Shen. Bioactive Thin Film of Acidic Fibroblast Growth Factor Fabricated by Layer-by-Layer Assembly, Bioconjugate Chemistry, 2005, 16, 1316-1322
  77. Weijun Tong, Changyou Gao*, Helmuth M?hwald. Manipulating the Properties of Polyelectrolyte Microcapsules by Glutaraldehyde Cross-Linking, Chemistry of Materials, 2005, 17, 4610-4616
  78. Bo Wang, Jie Feng, Changyou Gao*. Printing biomacromolecules on a bovine serum albumin precursor layer, Macromolecular Bioscience, 2005, 5(8): 767-774
  79. Weijun Tong, Wenfei Dong, Changyou Gao*, Helmuth M?hwald. Charge-Controlled Permeability of Polyelectrolyte Microcapsules. Journal of Physical Chemistry B, 2005, 109: 13159-13165
  80. Yi Hong, ChangyouGao*, Ying Xie, Yihong Gong, Jiacong Shen. Collagen-coated polylactide microspheres as chondrocyte microcarriers, Biomaterials, 2005, 26: 6305-6313
  81. Changyou Gao*, Helmuth M?hwald, Jiacong Shen. Thermosensitive poly(allylamine)-g-poly(N-isopropylacrylamide): synthesis, phase separation and particle formation, Polymer, 2005, 46 (12): 4088-4097
  82. Zhengwei Mao, Lie Ma, Changyou Gao*, Jiacong Shen. Preformed microcapsules for loading and sustained release of ciprofloxacin hydrochloride, Journal of Controlled Release, 2005, 104(1): 193-202
  83. Bo Wang, Changyou Gao*, Lili Liu. Loading and release behaviors of compressed polyelectrolyte multilayers for small dye molecules, Journal of Physical Chemistry B, 2005, 109, 4887-4892
  84. Zuwei Ma, Changyou Gao*, Yihong Gong, Jiacong Shen. Cartilage tissue engineering PLLA scaffold with surface immobilized collagen and basic fibroblast growth factor, Biomaterials, 2005, 26: 1253-1259
  85. Qinghe Zhao, Changyou Gao*, ,Jiacong Shen, Yu Li, Xiaobin Zhang. Incorporation of carbon nanotubes into hollow microcapsules using a removable template assembly, Macromolecular Rapid Communications, 2004, 25: 2014-2018
  86. Jie Feng, Bo Wang, Changyou Gao*, Jiacong Shen. Selective Adsorption of Microcapsules on Patterned Polyelectrolyte Multilayers, Advanced Materials, 2004, 16: 1940-1944
  87. Changyou Gao*, Bo Wang, Jie Feng, and Jiacong Shen. Irreversible Compression of Polyelectrolyte Multilayers, Macromolecules, 2004, 37: 8836-8839
  88. Bo Wang, Jie Feng, Changyou Gao*. Physical-co-chemical Multi-component Micro-patterns on Polymer Surface by Thermal Pressing Method, Chemistry of Materials, 2004, 16: 4859-4863
  89. Lie Ma, Changyou Gao*, Zhengwei Mao, Jie Zhou, Jiacong Shen. Biodegradability and cell-mediated contraction of collagen porous scaffolds: The effect of lysine as a novel cross-linking bridge, Journal of Biomedical Materials Research Part A, 2004, 71A(2): 334-342
  90. Jie Feng, Changyou Gao*, Bo wang, Jiacong Shen. A novel process for inking the stamp with biomacromolecule used in reactive microcontact printing, Colloids and Surfaces B: Biointerfaces, 2004, 36(3-4): 177-180
  91. Yabin Zhu, Changyou Gao*, Yunxiao Liu, Jiacong Shen. Endothelial cell functions in vitro cultured on poly(L-lactic acid) membranes modified with different methods, Journal of Biomedical Materials Research, 2004, 69 (3): 436-443
  92. Jie Feng, Changyou Gao*, Jiacong Shen. Micropatterning biomacromolecules on aldehyde-enriched polyester surfaces by a microtransfer technique, Chemistry of Materials, 2004, 16: 1319-1322. (SCI, EI)
  93. Yabin Zhu, Changyou Gao*, Xingyu Liu, Tao He, Jiacong Shen. Immobilization of Biomacromolecules onto Aminolyzed Poly(L-lactic acid) towards Acceleration of Endothelium Regeneration, Tissue Engineering, 2004, 10(1): 53-61
  94. Changyou Gao*, Helmuth M?hwald, Jiacong Shen. Enhanced biomacromolecule encapsulation by swelling and shrinking procedures, ChemPhysChem, 2004, 5(1): 116-120. (SCI)
  95. Lie Ma, Changyou Gao*, Zhengwei Mao, Jie Zhou, Jiacong Shen. Enhanced biological stability of collagen porous scaffolds by using amino acids as novel cross-linking bridges, Biomaterials, 2004, 25(15): 2997-3004
  96. Yabin Zhu, Changyou Gao*, Tao He, Jiacong Shen. Endothelium Regeneration on Luminal Surface of Polyurethane Vascular Scaffold Modified with Diamine and Covalently Grafted with Gelatin, Biomaterials, 2004, 25(3): 423-430
  97. Yabin Zhu, Changyou Gao*, Jianjun Guan, Jiacong Shen. Engineering Porous Polyurethane Scaffolds by Photo-Grafting Polymerization of Methacrylic Acid for Improved Endothelial Cell Cytocompatibility, Journal of Biomedical Materials Research Part A, 2003, 67A (4): 1367-1373
  98. Zuwei Ma, Changyou Gao*, Yihong Gong, Jiacong Shen. Paraffin spheres as porogen to fabricate poly(L-lactic acid) scaffolds with improved cytocompatibility for cartilage tissue engineering, Journal of Biomedical Materials Research B,2003, 67B(1): 610-617
  99. Lie Ma, Changyou Gao*, Zhengwei Mao, Jie Zhou, Jiacong Shen, Xueqing Hu, Chunmao Han. Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering, Biomaterials, 2003, 24(26): 4833-4841
  100. Zuwei Ma, Changyou Gao*, Yihong Gong, Jiacong Shen. Chondrocyte Behaviors on Poly-L-lactic acid (PLLA) Membranes Containing Hydroxyl, Amide or Carboxyl Groups, Biomaterials, 2003, 24(21): 3725-3730
  101. Changyou Gao*, Helmuth M?hwald, and Jiacong Shen. Soluble microcapsules assembled stepwise from weak polyelectrolytes using acid decomposable cores, Advanced Materials, 2003, 15(11): 930-933
  102. Changyou Gao*, Jianjun Guan, Yabin Zhu, Jiacong Shen. Surface Immobilization of Bioactive Molecules on Polyurethane Surface for Promotion of Cytocompatibility with Human Endothelial Cells, Macromolecular Bioscience, 2003, 3: 157-162
  103. Changyou Gao*, Stefano Leporatti, Sergio Moya, Edwin Donath, Helmuth M?hwald. Swelling and Shrinking of Polyelectrolyte Microcapsules in Response to Changes in Temperature and Ionic Strength, Chemistry, a European Journal, 2003, 9(4): 915-920
  104. Yabin Zhu, Changyou Gao*, Tao He, Xingyu Liu, Jiacong Shen. Layer-By-Layer Assembly to Modify Poly(L-Lactic Acid) Surface towards Improving Its Cytocompatibility to Human Endothelial Cells, Biomacromolecules, 2003, 4: 446-452
  105. Yabin Zhu, Changyou Gao*, Xingyu Liu, Jiacong Shen. Surface Modification of Polycaprolactone Membrane via Aminolysis and Biomacromolecule Immobilization for Promoting Cytocompatibility of Human Endothelial Cells, Biomacromolecules, 2002, 3: 1312-1319
  106. Zuwei Ma, Changyou Gao*, Yihong Gong, Jian Ji, Jiacong Shen. Immobilization of Natural Macromolecules on Poly-L-Lactic Acid Membrane Surface in Order to Improve Its Cytocompatibility, Journal of Biomedical Materials Research Part B, Applied Biomaterials, 2002, 63 (6): 838-847
  107. Changyou Gao*, Edwin Donath, Helmuth. M?hwald, Jiacong Shen. Spontaneous Deposition of Water-Soluble Substances into Microcapsules: Phenomenon, Mechanism, and Application, Angewandte Chemie International Edition, 2002, 41(20): 3789-3793
  108. Huiguang Zhu, Jian Ji, Rongyi Lin, Changyou Gao, Linxian Feng, Jiacong Shen. Surface engineering of poly(D,L-lactic acid) by entrapment of chitosan-based derivatives for the promotion of chondrogenesis, Journal of Biomedical Materials Research, 2002, 62(4): 532-539
  109. Changyou Gao*, Xingyu Liu, Jiacong Shen, Helmut M?hwald. Spontaneous deposition of horseradish peroxidase into polyelectrolyte multilayer capsules to improve its activity and stability, Chemical Communications, 2002, (17): 1928-1929
  110. Yabin Zhu, Changyou Gao*, Jiacong Shen. Surface modification of polycaprolactone with poly(methacrylic acid) and gelatin covalent immobilization for promoting its cytocompatibility, Biomaterials, 2002, 23(24): 4889-4895
  111. Huiguang Zhu, Jian Ji, Rongyi Lin, Changyou Gao, Linxian Feng, Jiacong Shen. Surface engineering of poly(DL-lactic acid) by entrapment of alginate-amino acid derivatives for promotion of chondrogenesis, Biomaterials, 2002, 23: 3141-3148
  112. C. Gao, E. Donath, S. Moya, V. Dudnik, H. M?hwald. Elasticity of Hollow Polyelectrolyte Capsules Prepared by the Layer-By-Layer Technique, The European Physical Journal E, 2001, 5: 21-27
  113. Changyou Gao, Stefano Leporatti, Sergio Moya, Edwin Donath, Helmuth M?hwald. Stability and Mechanical Properties of Polyelectrolyte Capsules Obtained by Stepwise Assembly of Poly(styrenesulfonate sodium salt) and Poly(diallyldimethyl ammonium) Chloride onto Melamine Resin Particles. Langmuir, 2001, 17: 3491-3495
  114. Changyou Gao, Stefano Leporatti, Edwin Donath, Helmuth M?hwald. Surface Texture of Poly(styrenesulfonate sodium salt) and Poly(diallyldimethylammonium chloride) Micro-Sized Multilayer Capsules: A Scanning Force and Confocal Microscopy study, Journal of Physical Chemistry B, 2000, 104 (30): 7144-7149



 

Conference List

  1. Changyou Gao. Gene Loaded Scaffolds for cartilage and skin regeneration, Hangzhou Symposium on Supramolecular Systems and Biomaterials, Oct. 30- Nov. 1, 2010, Hangzhou. Invited lecture, co-chair of the conference, session chair.
  2. Changyou Gao. Gene activated scaffolding materials for cartilage and skin regeneration, International Conference on Cellular & Molecular Bioengineering 2, Singapore, Aug. 2-4, 2010. Plenary lecture, P30-31.
  3. Wei Wang, Changyou Gao *. A new attempt to repair cartilage: hydrogel filled scaffolds, stem cells and gene therapy, Workshop on Tissue Inductive Materials, National Biomaterials Congress, April 15-18, 2010, Chengdu, China. Invited lecture.
  4. Jindan Wu, Huaping Tan, Changyou Gao*. Covalently Immobilized Protein Gradient Surface for Cell Distribution and Migration, JSPS A3 Foresight Program, 8th Seminar in Naha-Novel cell specific and pH-snesitive non-viral gene carrier system, Dec. 20-23, 2009, Naha, Okinawa, Japan. P 7-9, Oral lecture.
  5. Changyou Gao. Self-assembled microcapsules for drug loading and release, US-China Workshop for Early Career Chemical Scientists- New Materials, Oct. 27-29, Beijing, China. P51-53. Invited lecture.
  6. Changyou Gao. Self-assembled multilayer microcapsules with tailored structures and properties, The 2nd Asian Symposium on Advanced Materials, Oct. 11-14, 2009, Shanghai. P240, Keynote lecture, C-KN-02.
  7. Changyou Gao. Self-assembled microcapsules for drug loading and release, 2009 China-Korea Bilateral Symposium on Polymer Materials, July 12-15, 2009, Hangzhou, O-1, Invited lecture.
  8. Wei Wang, Zhengwei Mao, Lie Ma, Changyou Gao*. Facile technologies for fabricating bioactive scaffolds, The 6th China-Japan-Korea Foresight Joint Symposium on Gene Delivery and International Symposium on Biomaterials, Nov. 26-28, 2008, Sanya, P 66. Invited lecture.
  9. Changyou Gao*, Wei Wang, Lie Ma. Facile pathways for fabricating cell-compatible scaffolds, 2008 TERMIS–AP Chapter Meeting, 6/11-8/11, 2008, Taipei, P 70. Invited lecture, session Chair.
  10. Changyou Gao. Fabrication and biomedical applications of biocompatible polymer scaffolds, The 42nd IUPAC Word Polymer Congress (Macro 2008)-Polymers at Frontiers of Science and Technology, June 29- July 4, 2008, Taipei. No. 1239, P 256. Invited presentation.
  11. Changyou Gao. Multilayer nanofilms and microcapsules for biomedical applications, International Symposium on Polymer Chemistry, PC’ 2008, 2008.5.15-19, Hefei, China. P80. Invited presentation.
  12. Changyou Gao. Scaffolding materials for tissue regeneration, 2008 Chinese Academy of Sciences International Symposium on Advanced Polymer Materials, May 6-8, 2008, NingBo, P23, Invited.
  13. Changyou Gao. Manipulating the structure and properties of multilayer microcapsules, The International Symposium on Recent advances in Biotechnologies, April 7-9, 2008, Hangzhou, P 1-2, plenary lecture.
  14. Changyou Gao*. Biocompatible scaffolds for tissue engineering and regenerative medicine, International Conference on Cellular & Molecular Bioengineering (ICCMB), Dec. 10-12, 2007, Singapore. Invited presentation.
  15. C. Y. Gao,* J.D. Wu, H.P. Tan, L.H. Li. Surface Modification of Biomedical Polymers for Manipulating Cell Attachment and Growth, 1st Asian Biomaterials Congress (1st ABMC), Dec. 6-8, 2007, Tsukuba, Japan. P62, Invited presentation, Member of International Advisory Board.
  16. Changyou Gao,* Weijun Tong, Zhiqiang Feng, Feng Wang, Zhipeng Wang, Qinghe Zhao. Smart microcapsules with layered structure: from basic chemistry to potential applications, 9th International Symposium on Polymers for Advanced Technologies, 22-25, October 2007, Shanghai, China. P37. Session Chairperson; Invited presentation.
  17. Changyou Gao*. Biomedical Materials: From Basic Science to Potential Applications, NTU-ZJU Joint Research Seminar, Feb.8-9, 2007, Singapore, P10. Invited presentation.
  18. Changyou Gao*. Cytocompatible and cytoinductive biomaterials and scaffolds for tissue engineering and regenerative medicine. EU-China Workshop on Nanomaterials, Nov.6-8, 2006, Brussels, Belgium, Invited talk.
  19. Changyou Gao*. Cytocompatible and cytoinductive biomaterials and scaffolds for tissue engineering and regenerative medicine. Sino-Swiss Cooperation Symposium on Materials Science, Oct.30-Nov.2, 2006, Zurich, Switzerland, P14-16. Invited talk.
  20. Changyou Gao*. Chitosan based gene delivery system and particle internalization, Sino-German Forum on Nanoscience and Biomedicine, Oct. 12-15, 2006, Beijing. P4-5, Invited talk.
  21. Changyou Gao*, Weijun Tong, Bo Wang, Qinghe Zhao, Helmuth M?hwald. Microcapsules for drug delivery: from basic chemistry to potential applications. 1st Sino-German Frontiers of Chemistry Symposium, July 19-23, 2006, in Koster Seeon, Germany, p35. Invited talk.
  22. Changyou Gao*, Weijun Tonga, Helmuth M?hwald. Permeability control of multilayer microcapsules by charge interaction, International Symposium on Polymer Chemistry (PC’ 2006), 2006, 6, 7-11 Dalian, 54-55. Invited talk
  23. Changyou Gao*, Weijun Tong, Xingyu Liu, Jiacong Shen. Smart polyelectrolyte microcapsules: fabrication, properties and potential applications, International Symposium on Polymer Chemistry (PC’ 2004), 2004, Changchun, 102-103. Invited talk

Patent List

39 patents were authorized from State Intellectual Property Office of PRC.
 

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