Ren Qilong

Professor, Department of Chemical and Biochemical Engineering
Ph.D Supervisor

 

Phone: +86 571 8795 2773
Fax: +86 571 8795 2773
Email: renql@zju.edu.cn
Office: The Fourth Teaching Building

Zhejiang University, Yuquan Campus
38 Zheda Road
Hangzhou, China 310027

 

Other Appointments

Director, Department of Chemical and Biochemical Engineering
Deputy Director, National Laboratory of Secondary Resources Chemical Engineering
Main Founder, the new major of Pharmaceutical Engineering in Department of Chemical Engineering
 

Professional Activities


 

Education

Ph.D. –Zhejiang University, Chemical Engineering, 1998
M. S –Zhejiang University, Chemical Engineering, 1987,
B.S. –Zhejiang University, Polymer Chemical Engineering, 1982.

Working Experience

2000-present.,Professor of Chemical Engineering, Zhejiang University, China
1995-2000.Associate Professor of Chemical Engineering, Zhejiang University, China
1987-1995, Lecturer, Zhejiang University, China
1982-1987, Teacher,. Zhejiang University, China

Have conducted research works on proteins separation for one year (Oct. 1992 to Oct. 1993) at The Institute of Proteins, Osaka University, Japan, as an academic visitor.

 

Awards and Honors

The Second Prize, National Award for Invention, 2009
 

Research Interests

Separation methods of natural pharmaceuticals and their applications in industry;
Industrial Chromatography;
Adsorption separation engineering.
Supercritical fluids extraction and chromatography;
Ionic liquids: design and application;
Clean utilization of coal;
Biomass resources and energy
 

Current Projects

  1. Manufacturing process of natural high purity alpha-tocopherol(natural vitamin E), soybean isoflavones, sterols, soybean phospholipids and cholesterol ( Industrialization);
  2. Separation of chiral pharmaceuticals by supercritical fluid chromatography(NSFC, 29776040);
  3. Preparation of Vinorelbine( Industrialization);
  4. Purification of sodium thiocyanate by gel chromatography( Industrialization);
  5. Separation of EPA and DHA by supercritical fluid chromatography( Industrialization);
  6. Supercritical carbon dioxide fluid extraction of metal ions( NSFC,20676112);
  7. Selective separation of natural active homologous based on ionic liquids extraction;
  8. Key equipments and processes of ethyne production through coal cracking by plasma.
  9. Preparation of raffinose( Industrialization);
  10. The establishment of evaluation system for Nervous System Drug Pharmacodynamics and the new drug development(2006C13009);
  11. Simulated Moving Bed technology and its applications (Zhejiang Province Key Natural Science and Technology Fund);
  12. Green fixed-bed of acid / base catalysis in the pharmaceutical and fine chemical applications;
  13. High-efficient separation & preparation technology and equipment for the Functional Factors in Food.(National High-tech R&D Program ,863 Program, 2007AA100404);
  14. Key technology development of separation and preparation for the Functional Factors in Food (National Science and Technology Support Scheme, 2006BAD27B03).

Publication List

Selected Publications

  1. Yang, Q. W.; Zhang, H.; Su, B. G.; Yang, Y. W.; Ren, Q. L.; Xing, H. B. Volumetric Properties of Binary Mixtures of 1-Butyl-3-methylimidazolium Chloride + Water or Hydrophilic Solvents at Different Temperatures. J. Chem. Eng. Data. 2010, DOI: 10.1021/je900733j.
  2. Lei, H. J.; Bao, Z. B.; Xing, H. B.; Yang, Y. W.; Ren, Q. L.; Zhao, M. M.; Huang, H. H. Adsorption Behavior of Glucose, Xylose, and Arabinose on Five Different Cation Exchange Resins. J. Chem. Eng. Data. 2010, 55(2), 735-738.
  3. Xing, H. B.; Su, B. G.; Ren, Q. L. Yang. Y. W. Adsorption equilibria of artemisinin from supercritical carbon dioxide on silica gel. J. Supercritic. Fluid 2009, 49(2), 189-195.
  4. Yang, Q. W.; Xing, H. B.; Cao, Y. F.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Selective separation of tocopherol homologues by liquid-liquid extraction using ionic liquids. Ind. Eng. Chem. Res. 2009, 48(13), 6417-6422.
  5. Su, B. G.; Bao, Z. B.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Enantioseparation of paroxetine intermediate on an amylose-derived chiral stationary phase by supercritical fluid chromatography.J. Chromatogr. A 2009, 1216 (26), 5140-5146.
  6. Chen, W.; Su, B. G.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Solubilities of cholesterol and desmosterol in binary solvent mixtures of n-hexane plus ethanol. Fluid Phase Equilib.A 2009, 287(1), 1-6.
  7. Huang, H. H.; Zhao, M. M.; Ren, Q. L.; Yang, Y. W. Changes in inhibitory activity and secondary conformation of soybean trypsin inhibitors induced by tea polyphenol complexation.J. Sci. Food Agric. 2009, 89(14), 2435-2439.
  8. Wang, J. Y.; Su, B. G.; Su, Y.; Yang, Y. W. ; Ren, Q. L. LC Separation and Quantification of Tocopheryl Polyethylene Glycol Succinate and Tocopheryl Acid Succinate in TPGS Reaction Mixture.Chromatographia. 2009, 70(3-4), 551-555.
  9. Su, B. G.; Chen, W.; Xing, H. B.; Yang, Y. W.; Ren, Q. L. Phase Behavior and Micropolarity of Ammonium Carboxylate Perfluoropolyether Reverse Micelles in Supercritical Carbon Dioxide. J. Chem. Eng. Data. 2009, 54(6), 1884-1888.
  10. Xing, H. B.; Su, B. G.; Wang, Y. Y.; Yang, Y. W.; Ren, Q. L.; Xiao, W. G.; Lu, X. Y. Separation and Determination of Asiaticoside, Asiaticoside-B and Madecassoside in Centella asiatica Total Triterpenoid Saponins by HPLC.J. Liq. Chromatogr. Related Technol. 2009, 32(13), 1891-1900.
  11. Lu, X. B.; Xing, H. B.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Adsorption behavior of Penicillin G sodium onhydrophilic gel toyopearl HW-40F. J. Chem. Eng. Data. 2009, 54(3), 1052-1055.
  12. Lu, X. B.; Xing, H. B.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Separation of macromolecular impurities in Penicillin G sodium by gel filtration chromatography. J. Liq. Chromatogr. Related Technol. 2009, 32(7), 984-999.
  13. Yang, Q. W.; Wei, Z. J.; Xing, H. B.; Ren, Q. L. Bronsted acidic ionic liquids as novel catalysts for the hydrolyzation of soybean isoflavone glycosides. Catal. Commun. 2008, 9(6), 1307-1311.
  14. Bao, Z. B.; Su, B. G.; Ren, Q. L. Kinetic and equilibrium study of the enantioseparation of paroxetine intermediate on amylose and tartaric acid-based chiral stationary phases. J. Sep. Sci. 2008, 31(1), 16-22.
  15. Bao, Z. B.; Su, B. G.; Yang, Y. W.; Ren, Q. L. Enantioseparation of paroxetine precursors by HPLC on amylose and tartardiamide-based chiral stationary phases. J. Liq. Chromatogr. R. T. 2008, 31(8), 1147-1161.
  16. Yang, Y. W.; Dong, X. Y.; Jin, M. C.; Ren, Q. L. Rapid determination of polycyclic aromatic hydrocarbons in natural tocopherols by highperformance liquid chromatography with fluorescence detection. Food Chem. 2008, 110(1), 226-232.
  17. Su, B. G.; Xing, H. B.; Yang, Y. W.; Ren, Q.L. Solubility of oxymatrine in supercritical carbon dioxide. J. Chem. Eng. Data 2008, 53(7), 1672-1674.
  18. Su, B. G.; Xing, H. B.; Ren, Q. L. Solubilization of oxymatrine in water- in-supercritical carbon dioxide microemulsions. J. Chem. Eng. Data 2008, 53(8), 1705-1707.
  19. Chen, W.; Su, B. G ; Xing, H. B.; Ren, Q. L. Solubility of desmosterol in Five organic solvents. J. Chem. Eng. Data 2008, 53(11), 2715-2717
  20. Huang, M.; Xu, Y. J.; Lv, Q. L.; Ren, Q. L. Separation and purification of beta-carotene from chlorophyll factory residues. Chem. Eng. Technol. 2008, 31(6), 922-927.
  21. Jin, M. C.; OuYang, X.; Yang, Y. W.; Ren, Q. L. Quantification of tripdiolide in human whole blood by liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry. Talanta 2007, 72(2), 582-586.
  22. Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Determination of soyasaponins Ba and Bb in human serum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Chromatogr. B 2007, 846(1-2), 169-175.
  23. Yang, Y. W.; Jin, M. C.; Huang, M.; Su, B. G.; Ren, Q. L. Ultrasound-assisted extraction of soyasaponins from hypocotyls, and analysis by LC-ESI-MS. Chromatographia 2007, 65(9-10): 555-560.
  24. Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Determination of soyasaponins Ba and Bb in human serum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Chromatogr. B 2007, 846, 169-175.
  25. Bao, Z. B.; Wei, Z. J.; Su, B. G.; Ren, Q. L. Solubility of racemic paroxetine intermediate in supercritical carbon dioxide. J. Chem. Eng. Data 2006, 51(5), 1731-1734.
  26. Su, B. G.; Lv, X. B.; Yang, Y. W.; Ren, Q. L. Solubilities of dodecylpolyoxyethylene polyoxypropylene ether in supercritical carbon dioxide. J. Chem. Eng. Data 2006, 51(2), 542-544.
  27. Jin, M. C.; Yang, Y. W.; Su, B. G.; Ren, Q. L. Rapid quantification and characterization of soyasaponins by high-performance liquid chromatography coupled with electrospray mass spectrometry. J. Chromatogr. A 2006, 1108, 31-37.
  28. Lv, Y. B.;Wei, F.;Chen, B.; Ren, Q. L.; Wu, P. D. Modeling, sinmulation of a simulated moving bed for separation of phosphatidylcholine from soybean phospholipids. Chinese .Chem. Eng. 2006, 14(2), 171-177.
  29. Liu, B. J.; Yang, Y. W.; Ren Q. L. Parallel pore and surface diffusion of levulinic acid in basic polymeric adsorbents. J. Chromatogr. A 2006, 1132 (1-2), 190-200.
  30. Liu, B. J.; Ren, Q. L. Sorption of levulinic acid onto weakly basic anion exchangers: Equilibrium and kinetic studies J. Colloid Interf. Sci. 2006, 294 (2), 281-287.
  31. Zhou, J.; Ren, Q. L.; Wu, P. D. Chromatographic separation of fluoxetine hydrochloride enantiomers by cellulose chiral stationary phase. J. Liq. Chromatogr. R. T. 2005, 28 (20), 3229-3242.
  32. ? Zhang, Y. Y.; Yang, Y. W.; Jiang, Hailiang; Ren, Q. L. Quantification of soybean phospholipids in soybean Degummed oil residue by HPLC with evaporative light scattering detectrion. J. Liq. Chromatogr. R. T. 2005, 28(9), 1333-1343.
  33. Qian, G. P.; Yang, Y. W.; Ren, Q. L. Determination of artemisinin in Artemisia annua L. by reversed phase HPLC. J. Liq. Chromatogr. R. T. 2005, 28(5), 705-712.
  34. Yang, Y. W.; Su, B. G.; Yan, Q. H.; Ren, Q. L. Separation of naproxen enantiomers by supercritical/subcritical fluid chromatography. J. Pharm. Biomed. 2005, 39(4): 815-818.
  35. Yang, Y. W.; Wen, G. D.; Wu, C. J.; Ren, Q. L. Wu PD. Preparation of natural α-tocopherol from non-α-tocopherols. J. Zhejiang Univ. Sci. 2004, 5(12), 1524-1527.
  36. Yang, Y. W.; Wu, C. J.; Wang, X. D.; Huang, M.; Ren, Q. L. Purification of EPA-EE and DHA-EE with supercritical fluid chromatography. J. Chem. Eng. of Chinese Univ. 2004, 18(3), 293-296.
  37. Xing, H. B.; Yang, Y. W.; Su, B. G.; Huang, M.; Ren, Q. L. Solubility of Artemisinin in Supercritical Carbon Dioxide. J. Chem. Eng. Data 2003, 48, 330-332.
  38. Jiang, C. W.; Ren, Q. L.; Wu, P. D. Study on retention factor and resolution of tocopherols by supercritical fluid chromatography. J. Chromatogr. A 2003, 1005(1), 155-164.
  39. Huang, M.; Wang, X. D.; Xiong, R. T.; Wu, P. D.; Ren, Q. L. Determination of partial molar volumes of EPA and DHA ethyl esters in supercritical carbon dioxide. Chinese Chem. Lett. 2002, 13(1), 83-86.
  40. Lu, X. H.; Ren, Q. L.; Wu, P. D. Mathematical model of the dynamics of countercurrent chromatography. J. Zhejiang Uni. Sci. 2002, 3(2), 151-156