Chen Xinzhi

Professor, Department of Chemical Engineering
 

Phone: +86 571 8795 1615
Fax: +86 571 8795 1742
Email: xzchen@zju.edu.cn
Office: Room 3205, The Tenth Teaching Building

Zhejiang University, Yuquan Campus
38 Zheda Road
Hangzhou, China 310027
 

Other Appointments

Vice-Chairman, Institute of Chemical Engineering
 

Professional Activities

Member, Journal of Chemical Engineering of Chinese Universities Editorial Board
 

Education

Ph.D. – Zhejiang University, Chemical Engineering and Technology, 1989
M.S. –Zhejiang University, Chemical Engineering Thermodynamics, 1986
B.S. – Zhejiang University, Petrochemical Technology, 1983

Working Experience

1998-, Professor, Department of Chemical Engineering, Zhejiang University
1993-1998, Associate professor, Department of Chemical Engineering, Zhejiang University
1989-1993, Assistant professor, Department of Chemical Engineering, Zhejiang University
 

Awards and Honors

Zhejiang Provincial Science and Technology Award, First Prize, 2010Research Interests
1) Fine Chemicals and Their Synthetic Technology
2) Chemical Process Intensification
3) Applied Thermodynamics
 

Current Projects

1) National Natural Science Foundation(Chiral Synthesis of Indoline-2-Carboxylic Acids, No.20776127;Reactions and Mechanisms for a Green and Efficient Synthesis of Thiophenols, No. 21076183)
2) National Key Technology R&D Program (Greenization and Industrialization of the Preparation of α-Glucosidase Inhibitor, No. 2007BAI34B07)
3) Zhejiang Provincial Science and Technology Program (Development and Application of the Integration Technique for Reaction and Separation, No. 2008C01006-1)
Published Books
1) Xinzhi Chen, Zhenyun Cai, Wangming Hu, Chao Qian. Chemical Engineering Thermodynamics (3rd Edition). Chemical Industry Publisher, TQO13.1, ISBN978-7- 122-04773-1, 2009
2) Xinzhi Chen, Zhenyun Cai, Wei Xia. Solution to the Exercises of Chemical Engineering Thermodynamics. Scientific Press, ISBN 7-03-009538-3/O.1406, 2002.
3) Xinzhi Chen, Zhenyun Cai, Chao Qian. Instruction for Learning of Chemical Engineering Thermodynamics (1st Edition). Chemical Industry Publisher, TQO13.1, ISBN978-7- 122-10503-5, 2011
4) Xinzhi Chen and Anguo Ying, Ionic Liquids: Applications and Perspectives,”Chap.14 DBU Derived Ionic Liquids and TheirApplication in Organic Synthetic Reactions”, Edited by: Alexander Kokorin, ISBN978-953-307-248-7, pages305-330, InTech, Feb.,2011
Selected Publications
1) Yi-Feng Lai, Hui Zheng, She-Jie Chai, Peng-Fei Zhang and Xin-Zhi Chen, Lipase-catalysed tandem Knoevenagel condensation and esterification with alcohol cosolvents, Green Chem., 2010, 12, 1917-1918
2) Zhen Yu Cai, Ming Qiao Zhu, Yue Tang, Yi Liu, Huan Dai, Xin Zhi Chen, Chao Hong He, Carbon-Supported Gold Catalyst Modified by Doping with Ag for Cyclohexene Oxidation, Advanced Materials Research, 2011,v236-238, 3046-3050
3) Li Ji, Chao Qian, Mei-xin Liu, Xin-zhi Chen, Highly Efficient Nitration of Phenolic Compounds Using Oxalic Acid/Nitrates under Solvent-free Condition, J. Chem. Res, 2011,35(2)101-103
4) Bao-Yu Hao, Jin-Qiang Liu, Wei-Han Zhang , Xin-Zhi Chen, Novel Synthesis of cis-(3R,4R)-N- Boc-4-methyl-3-methyl- aminopiperidine with an asymmetric approach, Synthesis, 2011,(8),1208-1212
5) Chao Shen , Fangyi Shen , Haijun Xia, Pengfei Zhang, Xinzhi Chen, Carbohydrate-derived alcohols as organocatalysts in enantioselective aldol reactions of isatins with ketone, Tetrahedron: Asymmetry, 2011, 22,708-712
6) Shao Shen, Hui Zheng, Pengfei Zhang, Xinzhi Chen, Synthesis of Some Novel Glucosyl Triazoles from 2,3,4,6-Tetra-O-pivaloyl- D-glucopyranosyl Azide, Journal of Carbohydrate Chemistry, 2010,29,155–163
7) Chao Shen , Haijun Xia , Hui Zheng Pengfei Zhang and Xinzhi Chen, Synthesis of novel carbohydrate-based iminophosphinite ligands in Pd-catalyzed asymmetric allylic alkylations, Tetrahedron: Asymmetry, 2010, 21,1936–1941
8) Ling Gong, Chao Qian,Xinzhi Chen, Synthesis of 3-acetyl-6-(o-methyl benzoyl)-N- ethylcarbazole, Res Chem Intermed ,2010, 36(4):383-387
9) Hangeng Chen, Tao Zhang, Chao Qian, Xinzhi Chen, A novel method for N-alkylation of aliphatic amines with ethers over γ-Al2O3,Chemical Papers, 2010,64 (4) 537–540
10) Shaodong Zhou, Xinzhi Chen, Chao Qian, Quantum chemical modeling of the epoxidation with hydrogen peroxide catalyzed by Mn(III): Mechanistic insight, Chemical Physics Letters, 2010,488,44-49
11) An-Guo Ying, Li-Min Wang, Le-Le Wang, Xin-Zhi Chen, and Wei-Dong Ye, Green and efficient Knoevenagel condensation catalysed by a DBU based ionic liquid in water, J. of Chem. Res., 2010,1, 30-33
12) Chao Qian, Tao Zhang, Shiqing Pi, and Xinzhi Chen, Solubility of Canthaxanthin in Pure Solvents from (293.15 to 343.15) K, J. Chem. Eng. Data,2009, 54 (3), 1115-1116
13) Jin-Qiang Liu, Chao Qian, Xin-Zhi Chen, A Facile Chiral Pool Synthesis of (S)-6-Nitroindoline-2-carboxylic Acid from L-Phenylalanine, SYNTHESIS, 2010,(3),403-406
14) Tao Zhang, Ziguo Pan, Chao Qian, Xinzhi Chen, Isolation and purification of D-mannose from palm kernel, Carbohydrate Research, 2009,344,1687–1689
15) An-Guo Ying, Li-Min Wang, Hong-Xia Deng, Jian-Hui Chen, Xin-Zhi Chen, and Wei-Dong Ye, Green and efficient hetero-Michael additions of aromatic amines to α,β-unsaturated ketones catalyzed by DBU based task-specific ionic liquids without solvent, AKIVOC, 2009 (xi) 288-298
16) Liu Jinqiang, Qian Chao and Chen xinzhi, A green synthesis of phenyl vinyl sulfoxide, Research on Chemical Intermediates, 2009,35(2)137-144
17) Chao Qian, Ling Gong and Xinzhi Chen, Preparation of optical active aliphatic a-amino acid from fatty acid: synthesis of L-norvaline and D-norvaline, Research on Chemical Intermediates, 2009, 35(1):117~121
18) An-Guo Ying, Luo Liu, Guo-Feng Wu, Gang Chen, Xin-Zhi Chen, Wei-Dong Ye, Aza-Michael addition of aliphatic or aromatic amines to α,β-unsaturated compounds catalyzed by a DBU-derived ionic liquid under solvent-free conditions, Tetrahedron Letters, 2009,50:1653~1657
19) Ying An-guo, Luo Liu, Wu Guo-feng, Chen Xin-zhi, Ye Wei-dong, Chen Jian-hui and Zhang Kai-yuan, Knoevenagel Condensation Catalyzed by DBU Br?nsted Ionic Liquid without Solvent, Chem. Res. Chinese Univ., 2009, 25(6), 876-881
20) Chao Qian, Yan Liu, Xinzhi Chen, Improved Synthesis of 1-[Hexahydrocyclopenta[c] pyrrol-2(1H)-yl]-3- (4-methylbenzenesulfonyl) urea, Journal of Chemical Research, 2008,NOV., 635–636
21) Qianchao, Liu Jinqiang and Chen Xinzhi, Preparation of Nitroanilines by Ammolysis of Multinitrobenzenes, Synth. Commun., 2008,38,2782~2786
22) Qianchao, Liu Jinqiang and Chen Xinzhi, Preparation of N-alkylation-3,5-dinitroanline by Amination of 1,3,5-Trinitrobenzenes, Journal of Chemical Research, 2008,2,70~71
23) Qianchao, Pi Shiqing, Chen Xinzhi, Improved Synthesis of Methyl 3-Oxo-2,6,6- Trimethylcyclohex-1-ene-1-Carboxylate, an A-Ring Intermediate for (±)Strigol, Journal of Chemical Research, 2007,8,494~496
24) Yihui Bai, Xinzhi Chen, A mild synthesis of a,a'-[iminobismethylene] bis[6-fluoro-3,4- dihydro-2H-1-benzopyran-2-methanol, Journal of Chemical Research, 2006, (12), 807-808
25) Shi Xiaohua, Zhou Cairong, Gao Yuguo and Chen Xinzhi , Measurement and Correlation for Solubility of (S)-(+)-2,2- Dimethylcyclopropane Carbox Amide in Different Solvents, Chinese J. Chem. Eng. 2006,14(4):547~550
26) Wang, Xiao-Zhong; Chen, Ying-Qi; Jiang, Xi-Kui; Chen, Xin-Zhi; Li, Zhan-Ting, Hydrogen-bonding-induced planar, rigid, and zigzag oligoanthranilamides. Synthesis, characterization, and self-assembly of a metallocyclophane, Journal of Organic Chemistry
2004,69(19):6221~6227
27) Chen Xinzhi, Wang Lianwei, Hou Yujun(Y.C.Hou), A Perfect Shape Factor Corresponding States Principle for Pure Non-Polar and Polar Fluids, Chinese J. of Chem. Eng., 2001,9(4):421~426
 

Conference List

1) Xinzhi Chen, Qian Zhao, Chao Qian, Teaching Chemical Engineering Thermodynamics with Aspen-Plus------Phase Equilibrium Calculations for Mixtures, 2011 Int. Conf. on Fuzzy System and neural Computing(FSNC2011, Hong Kong, China, Feb. 20-21,2011), Edited by Tan Honghua, Vol.7,215-217,2011
Authorized Patents
1) Xinzhi Chen, Lanlan Sha, Chao Qian. Method for synthesizing 3-methoxy nitrobenzene, CN101250109, 2008. 200810060253.2, Issue Date, 2011.05.04.
2) Xinzhi Chen, Shuai Wang, Xiaoxiang Chen, Xu Zhang. Piping production process of N-(2-hydroxyethyl)-beta-D-pyran glucosamine. CN101284852, 2008.10.5. 200810062153.3, Issue Date, 2011. 05.04.
3) Xinzhi Chen, Ling Gong, Yan Liu, Chao Qian. N-amino-1,2-cyclopentanediformylimine and preparation method thereof, CN101235011, 2008. ZL200810060128.1, Issue Date,2010.2.24
4) Xinzhi Chen, Shuai Wang, Xu Zhang, Xiaoxiang Chen. Method for canalization preparation of N-butyl-beta-D-glucopyranose amine, CN101314610, 2008. ZL200810062674.9, Issue Date, 2010.12.30
5) Xinzhi Chen, Shaodong Zhou. Preparation method for 3-methoxy-N-methyldiphenylamine, CN101343238, 2008., ZL200810120382.6 ,Issue Date, 2010.12.15
6) Xinzhi Chen, Haijiang Zhang, Chao Qian. Method for synthesizing 3-amido-1,2-propanediol by pipe reactor, CN101250115, 2008,ZL200810060255.1, Issue Date,2010.09.08
7) Xinzhi Chen, Yan Liu, Lanlan Sha. Method for synthesizing 3,3'-dimethoxy diphenylurea, CN101250139, 2008,ZL200810060910.3, Issue Date, 2010.09.15
8) Xinzhi Chen, Chao Qian. Synthesis method of chiral norvaline, CN101007772, 2008.,ZL 200710066960.8, Issue Date, 2010.05.26
9) Xinzhi Chen, Tao Zhang, Chao Qian. Synthesis proces sof N-methyl morpholine, CN101066955, 2007, 200710069194.0, Issue Date, 2009.09.30
10) Xinzhi Chen, Ling Gong, Chao Qian. Method for synthesizing N-ethoxythioformylglycine ethyl ester, CN101121682, 2007, ZL200710070635.9, Issue Date, 2010.05.26
11) Xinzhi Chen, Lanlan Sha. Method for synthesizing veratric acid, CN101092351, 2007, 200710069745.3, Issue Date, 2010.05.26
12) Xinzhi Chen, Chao Zhang, Ling Gong, Xueping Yu, Xiaogang Chu. Method for synthesizing phenylethene /acrylonitrile/ N-phenyl maleimide terpolymer by one-step method, CN101081886, 2007, ZL200710069041.6, Issue Date, 2009.06.03
13) Xinzhi Chen, Jianrong Gao, Chao Qian, Xiaoyuan Mao. Method and device for preparing 1-aminoanthraquinone, CN101016250, 2007,ZL200710067509.8, Issue Date, 2009.2.25
14) Peiren Fan, Bin Fan, Junfei Zhu, Xinzhi Chen, Yinge Li, Wei Liu. Production method of m-bromophonol and production device thereof, CN100999446, 2007,ZL200710066702.X, Issue Date, 2010.05.26
15) Xinzhi Chen, Yihui Bai. Process of racemizing 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-formic acid, CN1974565, 2006, ZL200610155118.7, Issue Date, 2009.5.27
16) Xinzhi Chen, Chao Qian. Method for synthesis of L-norvaline, CN1962613, 2006, ZL200610154622.5, Issue Date, 2008.10.22
17) Xinzhi Chen, Chao Qian. Method for synthesizing D-norvaline using n-pentanoic acid, CN101007774, 2006, ZL200710066959.5, Issue Date, 2009.7.22
18) Xinzhi Chen, Chao Qian. [2-(2-Diisopropylamino-ethylamino)-ethyl]-diisopropyl-amine, and synthetic method and use thereof, CN101058542 , 2006, ZL200610154568.4, Issue Date, 2010.101.6
19) Xinzhi Chen, Yehua Su. Sulfonation reaction device for sulfur trioxide, CN1944402, 2006, ZL200610053933.2, Issue Date, 2008.11.19
20) Xinzhi Chen, Jinqiang Liu. Synthetic method for secondary butylamine, CN1900048, 2006, ZL200610052532.5, Issue Date, 2008.4.30
21) Xinzhi Chen, Jinqiang Liu. Synthetic method for cyclohexylamine, CN1900049, 2006, ZL200610052530.6, Issue Date, 2009.8.19
22) Xinzhi Chen, Chao Qian. Production method of N-ethyl iso penlyl amine and its device, CN1869001, 2006, ZL 200610052134.3, Issue Date, 2007.12.5
23) Jiangang Shi, Yaguang Wang, Xinzhi Chen, Chao Qian, Yehua Su. Process for synthesizing methyl acryloyl-(N,N-dimethyl propylene diamine) and device therefor, CN1837188, 2006, ZL200610050465.3, Issue Date, 2009.2.11
24) Jiangang Shi, Yaguang Wang, Xinzhi Chen, Chao Qian. Synthesis method of butadiene morpholine, CN1824659, 2006, ZL200610050100.0, Issue Date, 2008.6.4
25) Xinzhi Chen, Yanlei Chen. Synthesis method of N-substituted-3-amidopyrrolidine and its bihydrochlorate, CN1733720, 2005, ZL200510060483. 5, Issue Date, 2007.8.15
26) Xinzhi Chen, Guoquan Zhou. Process for synthesizing 2-p-trifluoro toluene-4-methyl-5-thiazolyl ethyl formate, CN1721414, 2005, ZL200510050092. 5, Issue Date, 2008.4.23
27) Xinzhi Chen, Chao Qian. S-(-)-indolyl-2-carboxylic acid synthesizing method, CN1709871, 2005, ZL200510049887.4, Issue Date, 2008.6.4
28) Xinzhi Chen, Weizhou Liang. Method for synthesizing 1-methyl-2-amine ethyl pyrrolidine, CN1660805, 2004, ZL200410099212.6, Issue Date, 2007.2.14
29) Xinzhi Chen, Shiqing Pi. Method for isomerizating 1, 4-dichloro-2-butylenes from syn form to anti form, CN1660729, 2004, ZL200410099211.1, Issue Date, 2006.8.9
30) Xinzhi Chen, Chao Qian. Process for synthesizing N, N-diisopropyl ethylenediamine, CN1634856, 2004, ZL200410067359.7, Issue Date, 2006.3.15
31) Xinzhi Chen, Xiaohua Shi, Fangming Jin, Chengming Li. Method ofr synthesizing S-(1)-2.2 dimethylcyclopropane formamide, CN1562962, 2004, ZL200410017680.4, Issue Date, 2006.7.5
32) Xinzhi Chen, Chao Qian. Process and apparatus for producing o-phenylenediamine, CN1594279, 2004, ZL200410025783.5, Issue Date, 2006.9.13
33) Xinzhi Chen, Chao Qian. Method for synthesizing pivalaldehyde, CN1562931, 2004, ZL200410017258.9, Issue Date, 2006.4.19